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Gain-of-Function Mutations in the KATP Channel (KCNJ11) Impair Coordinated Hand-Eye Tracking

Figure 3

Comparison of visually-guided and blanked tracking performance of patients with PNDM and iDEND.

Scatter plots showing discrepancy errors of iDEND patients (A, n = 6) and PNDM (B, n = 7) patients and their matched controls (Ctr), as indicated, on the linear tracking task with target blanking. The visually guided (first and last) and blanked (middle) segments of this task were analysed separately. Red bars indicate the median error. Discrepancy errors of iDEND patients were significantly higher than controls in segments 2 and 3. **, p<0.01 post-hoc Mann-Whitney U-tests. There were no differences between PNDM patients and controls in any of the three segments (Kruskal-Wallis test).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0062646.g003