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Quantitatively Different, yet Qualitatively Alike: A Meta-Analysis of the Mouse Core Gut Microbiome with a View towards the Human Gut Microbiome

Figure 6

Number of GM taxa shared between collated categories of humans and mice on both, phylum (A) and genus (B) level.

600000 high quality 16s rRNA reads used to represent each category were annotated to the Ribosomal Database Project (RDP, http://rdp.cme.msu.edu/) database. A cut off threshold for the low abundant taxa = 0.19%. Whenever a given taxon was present in both categories but the value for one or both was bellow the threshold level the label was kept and classified as shared. A) Phylum Deferribacteres was unique for the mouse category what reduced similarity between categories to 90%. B) Genus Mucispirillum unique for mouse category was the only representative of phylum Deferribacteres. Human GM cluster contained 9 unique genera groups, namely Faecalibacterium, Mitsuokellla, Megasphera, Dialister, Asteroleplasma, Succinivibio, Sutterella, Paraprevotella and Phascolarctobacterium (source: Table S1).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0062578.g006