The Complement Anaphylatoxin C3a Receptor (C3aR) Contributes to the Inflammatory Response in Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice
Figure 7
Cytokine profile of C3ar-/- vs. WT BALB/c and B6 mice in DSS colitis.
Cytokine levels were measured in tissue homogenates using a bead-based immunoassay. The data shown are means ± SEM from n = 3 (WT, H2O), n = 10 (WT, DSS), n = 5 (C3ar-/-, H2O), and n = 11 (C3ar-/-, DSS) mice for BALB/c, and n = 6 (WT, H2O), n = 10 (WT, DSS), n = 4 (C3ar-/-, H2O) and n = 11 (C3ar-/-, DSS) mice for C57BL/6. n.s., not significant; *, p<0.05; **, p<0.01; ***, p<0.001.