Phosphoinositide 3-Kinase Dependent Inhibition as a Broad Basis for Opponent Coding in Mammalian Olfactory Receptor Neurons
Figure 1
Physico-chemical representation of odorants used in the study.
A set of 38 physico-chemical descriptors was generated using CHEMMINE Tools. Odorants are color coded according to their main chemical functional groups. The group of assorted odorants includes aliphatic acids, ketones, heterocyclic compounds and lactones. Principal component analysis (PCA) of all odorants used in the study is based on their physico-chemical descriptors. The first two principal components are shown; values in parentheses refer to the proportion of the observed variance in the data that was explained by PC1 and PC2. 42 odorants labeled with dots including a subset of 9 odorants (black diamonds) used to perform a focused analysis of the ORN response profiles. Additional 8 naturally occurring major components of the tomato odor (open circles) were also included in the dataset.