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Increased Prefrontal and Parahippocampal Activation with Reduced Dorsolateral Prefrontal and Insular Cortex Activation to Food Images in Obesity: A Meta-Analysis of fMRI Studies

Figure 2

Axial (z), coronal (y), saggital (x) views of decreased activation to food images in fMRI studies of obese/overweight (versus healthy controls) - excluding Region of Interest Studies - FDR corrected, p<0.05 for multiple comparisons, cluster size >100 mm3.

Left: reduced activation in the left dorsolateral prefrontal cortex (LDPFC); reduced activation in the left insular cortex.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0060393.g002