Inversin/Nephrocystin-2 Is Required for Fibroblast Polarity and Directional Cell Migration
Figure 4
Inversin affects the activity of the Rho GTPases.
Activity of Rac-1, RhoA and Cdc42 was determined by pull-down in migrating inv+/+ and inv−/− MEFs 30 min (A) or 4 h (B) after scratch. Histograms represent the mean ± S.E.M. of three independent experiments.