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Chronic Treatment with the GLP1 Analogue Liraglutide Increases Cell Proliferation and Differentiation into Neurons in an AD Mouse Model

Figure 4

Quantification of BrdU positive cells in the SGZ.

Chronic treatment with liraglutide increases cell proliferation in both wild type and APP/PS1 animals regardless of age. Quantification of Ki67 immunoreactive cells in the SGZ. Chronic treatment with liraglutide increases endogenous cell proliferation in both wild type and APP/PS1 animals regardless of age. *p<0.05, **p<0.01 compared with saline control. Values are expressed as mean ± SEM (n = 6).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0058784.g004