Multi-Allelic Major Effect Genes Interact with Minor Effect QTLs to Control Adaptive Color Pattern Variation in Heliconius erato
Figure 4
F2-Not9 linkage map and overall QTL analysis.
(A) F2-Not9 linkage map and overall QTL analysis of the H. himera×H. erato notabilis cross showing the 20 autosomal and two sex linkage groups generated with AFLP and co-dominant anchor loci (Tables S5, Table S6, Table S7, and Table S8). Numbers of the left side represent distance in cM rounded to the closest integer value, while letters on the right side represent marker names. Approximate positions of major color pattern genes (Sd-LG 10, D-LG 18, Cr-LG 15) are indicated with a black square within each linkage group. Vertical bars next to the chromosomes represent QTL regions with colors corresponding to phenotypes measured: red bars = redness; white bars = whiteness; grey bars = Big-Spot (BS); and black bars = Not-Spot (NS). (B) Pie charts show the relative contributions of individual markers to the total variance explained when all significant QTLs were analyzed under the best model (additive or epistatic). Note that F2-Not9 LG 1, LG 10, LG 18 and LG 15 correspond to LG 4, LG 3, LG 6 and LG 2 in Kapan et al. (2006) and to LG 1, LG 10, LG 18 and LG 15 in Jiggins et al. (2005) respectively. Linkage analysis and autosomal LG numbers for the F2-NotF29 reference map are arranged with the same numbers as H. melpomene when homology could have ben established.