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Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation

Figure 1

Effect of andrographolide (Andro) and taxifolin (Taxi) on the growth of DU145 cells.

The cells were treated with a range of concentrations of (A) Andro and (B) Taxi for the indicated period of time and cell proliferation was monitored by MTT assay. The data from three independent experiments were expressed as percentage of viability compared to the vehicle control (DMSO). Values are mean ± s.d.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0054577.g001