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Sabiporide Improves Cardiovascular Function, Decreases the Inflammatory Response and Reduces Mortality in Acute Metabolic Acidosis in Pigs

Figure 3

Changes in pulmonary arterial pressure and pulmonary vascular resistance.

Pulmonary arterial pressure and vascular resistance rose in controls with lactic acid infusions and remained elevated throughout the study. The increase in both parameters was blunted with sabiporide. All values are the mean ± SD. N = 5–6. *p<0.05 vs. the control group; #p<0.05 vs. the baseline value.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0053932.g003