Dab2IP GTPase Activating Protein Regulates Dendrite Development and Synapse Number in Cerebellum
Figure 7
Delayed Purkinje cell dendrite outgrowth in Dab2IP KD mice.
(A) Immunohistochemical staining of cerebellar Purkinje cells with anti-calbindin antibody at various postnatal ages (P5, P8 and P14). Scale bar: 50 µm. (B) Measurement of PC dendritic tree length on lobule IV/V in WT (N = 3, 210 observations) and Dab2IP KD (N = 3, 210 observations) littermates at P5, P8 and P14. Values are expressed as means ± S.D. *, p<0.05; **, p<0.01, student’s t-test.