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Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation

Figure 5

Cerebrocortical blood flow and arterial blood gas tensions during stepwise hypoxia/hypercapnia.

Cerebrocortical blood flow (A and B, expressed as percentage of baseline levels) and arterial blood-gas tensions (C and D) are shown before (Baseline) and during mild, moderate and severe hypoxia/hypercapnia before (○) and after (•) intravenous injection of 10 mg kg−1 AM-251 or its vehicle. Values are mean ± SEM, *P<0.05, **P<0.01 versus “Before AM-251”, n = 4–12.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0053390.g005