Frondoside A Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis
Figure 3
Frondoside A induces regression of established LNM35 xenografts.
A) & B) Tumor volume of LNM35 xenografts inoculated subcutaneously in nude mice and treated with Frondoside A (0.01 and 1 mg/kg, intra-peritoneal injections, respectively) or control carrier solution alone, for a total of 25 days. Data points represent the mean ± S.E.M. of 6 mice per group. C) & D) Tumor weight obtained from the same control and treated nude mice. Data points represent the mean ± S.E.M. of 6 mice per group. Columns, mean; bars, S.E.M. E) & F) Body weight of these mice. Data points represent the mean ± S.E.M. of 6 mice per group. *Significantly different at P<0.05.