Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice
Figure 2
Analysis of selenoprotein mRNA expression in colonic epithelia of wild type allelic (Sep15+/+) and Sep15 knockout (Sep15−/−) mice.
Mice were maintained on 0, 0.1 or 2.0 µg selenium/g diet and mRNA levels were measured using real-time RT-PCR. Values are means±SEM; N = 4 per genotype per diet. Letters indicate statistically significant differences (two-way ANOVA).