Requirement of Plasminogen Binding to Its Cell-Surface Receptor α-Enolase for Efficient Regeneration of Normal and Dystrophic Skeletal Muscle
Figure 4
Inhibitors of α-enolase/plasminogen binding inhibits MPCs proliferation and migration.
A. Proliferation of MPCs in the presence of MAb11G1 or EACA by the MTT proliferation assay. Results are mean +/− SEM (error bars) of quadriplicates. * P<0.01. B. MPCs migration in Transwells chambers, in the presence of MAb11G1 or EACA. Results are expressed as a percentage of control MPCs migration. Results are mean +/− SEM (error bars) of three different experiments. ** P<0.05.