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A Pilot Study of Morphometric Analysis of Choroidal Vasculature In Vivo, Using En Face Optical Coherence Tomography

Figure 6

Qualitative Choriocapillaris Assessment Comparing C-Scans and B-Scans (Example 2).

Comparing another example of control (top panel), early age-related macular degeneration (AMD, middle panel) and reticular (bottom panel) patients, reveals qualitatively different appearance of representative C-scans obtained just below the retinal pigment epithelium in reticular groups (bottom right) than in the control and AMD groups (top right and center right, respectively). Red boxes on the B-Scans (left) show magnified and colorized selected areas of choroidal vasculature from the regions contained by the smaller red boxes on the C-Scans (right) for each group. Blue boxes on the B-Scans (left) show magnified areas of selected stroma from the regions contained by the smaller blue boxes on the C-Scans (right). Stromal sections demonstrate more patchy whitish regions in the RPD group (bottom panel) as compared to the control and AMD groups (top and middle panels) but similar vessel density due to the presence of larger vessels.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0048631.g006