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Apocynin-Treatment Reverses Hyperoxaluria Induced Changes in NADPH Oxidase System Expression in Rat Kidneys: A Transcriptional Study

Figure 7

Immuno histochemical staining of paraffin embedded kidney sections of HLP treated rats.

(A) Osteopontin (Opn) associated with crystal deposits, Single arrows show staining of crystal deposits while double arrows point to staining of epithelial cells of the adjoining renal tubular epithelia. (B) Double arrows point to strong staining for the monocyte chemoattractant protein (Mcp-1) in renal tubular epithelial cells (C) Staining for Nox-4 in tubular epithelial cells (D) Staining for Nox-2 in both tubular cells as well as interstitium and (E) general cytosolic staining for p47 in tubular epithelial cells.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0047738.g007