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Mycoplasma pneumoniae Large DNA Repetitive Elements RepMP1 Show Type Specific Organization among Strains

Figure 3

Model of two proposed recombination events.

A and B. Chromosomal region MPN129-MPN140 in M. pneumoniae M129. Position, length and orientation of all genes are presented and color-coded as above (arrows). C. Identification of sReps within MPN130, MPN137 and MPN138. Short repeats B (green arrows labeled B) were identified within both intergenic regions surrounding MPN130. Analyses revealed copies of sRepD and sRepE (red and blue arrows labeled D and E, respectively). Corresponding sReps involved in homologous recombination are connected by dotted lines. A diagram illustrates exchange of chromosomal regions during homologous recombination. D. Chromosomal regions after homologous recombination. Coding regions of three RepMP1-genes with rearranged domains are shown. sRepBs presumably involved in sequence deletion are indicated (asterisks). E. Deletion of two RepMP1-genes. Deleted region containing two RepMP1-genes (dotted loop) and implicated sRepB (green arrow) are represented. F. Chromosomal region MPN129-MPN140 in S1. Detailed depiction of MPN129-MPN131 and MPN138/7 regions and organization of the chromosomal region are presented.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0047625.g003