Role of Smad Proteins in Resistance to BMP-Induced Growth Inhibition in B-Cell Lymphoma
Figure 6
Expression of inhibitory SMADs in lymphoma cells.
(A) Real-time RT-PCR analysis of SMAD6 and SMAD7 expression in lymphoma cell lines, relative to their expression in the osteogenic sarcoma cell line Saos-2 (SMAD6; means ± SD, n = 2) or human fetal brain tissue (SMAD7; means ± SD, n = 5). (B) Relative expression of inhibitory SMADs across NHLs (left of line) and in normal B-cell populations (right of line) obtained from a gene expression data set from Basso et al. [16].