Recovered Patients with Stevens–Johson Syndrome and Toxic Epidermal Necrolysis Maintain Long-Lived IFN-γ and sFasL Memory Response
Figure 8
sFasL mAb blocking decreased the percentage of apoptotic keratinocytes. HaCat cells were incubated with culture medium containing 10% PBMC supernatants, the neutralizing anti-FasL mAb (NOK-2), the negative control mAb for 24 hours.
Annexin V staining showed that the inhibitory anti-FasL mAb reduced the number of apoptotic cells in a dose-dependent manner. *P<0.05.