Intravenous Grafts Of Amniotic Fluid-Derived Stem Cells Induce Endogenous Cell Proliferation and Attenuate Behavioral Deficits in Ischemic Stroke Rats
Figure 5
Enhanced endogenous cell proliferation and neuronal differentiation in the SVZ and DG following AFS cell transplantation.
Ki67 (A, E, I, M) and MAP2 (B, F, J, N) staining revealed an apparent increase in the number of positive cells in the SVZ (A-H) and DG (I-P) of the AFS cell-transplanted stroke animals (E-H, M-P) compared to the vehicle-infused stroke animals (A-D, I-L). Ki67 and MAP-2 double-positive cells are shown in panels: D, H, L, and P. Green: Ki67, Red: MAP2, Blue: Hoechst. Scale bar = 75 µm.