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Two-Photon Compatibility and Single-Voxel, Single-Trial Detection of Subthreshold Neuronal Activity by a Two-Component Optical Voltage Sensor

Figure 10

Properties of fAP and f-EPSP recorded from subcompartments of granule cells. A. Left:

Comparison of fAP amplitudes recorded from granule cell somata at 25°C (n = 12) and 35°C (n = 14). Right: Comparison of f-EPSP amplitudes recorded from somata of granule cells at 25°C (n = 8) and 35°C (n = 10). B. Left: Comparison of fAP width at 25°C and 35°C. Right: Comparison of SNR at 25°C and 35°C. C. Left: Pair-matched comparisons of optically recorded fAP amplitude between the soma and dendritic claws of granule cells (n = 7) recorded at 35°C. Right: Pair-matched comparisons of optically recorded f-EPSP amplitude between the soma and dendritic claws of granule cells (n = 7). D. Left: Pair-matched comparisons of fAP widths between the soma and dendritic claws. Right: Pair-matched comparisons of SNR of f-EPSPs between the soma and dendritic claws.

Figure 10

doi: https://doi.org/10.1371/journal.pone.0041434.g010