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Comparison of the Predicted Population Coverage of Tuberculosis Vaccine Candidates Ag85B-ESAT-6, Ag85B-TB10.4, and Mtb72f via a Bioinformatics Approach

Figure 2

Supertype Class II HLA-DRB1 alleles.

A comparison of the median number of Ag85B-ESAT-6, Ag85B-TB10.4, and Mtb72f vaccine epitopes predicted to bind to each of the eight HLA-DRB1 supertype alleles. Median and interquartile ranges of the epitopes predicted to bind by each of the eight prediction programs used are shown.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0040882.g002