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C/EBP Homologous Protein (CHOP) Deficiency Aggravates Hippocampal Cell Apoptosis and Impairs Memory Performance

Figure 7

Neuronal living cells in hippocampus of wild type and CHOP−/− mice.

Tunicamycin (0.1 mg/ml) were intracerebroventricular injected in the hippocampus of wild type C57BL/6J (W; A) and CHOP−/− (B) mouse for 5–7 days. Neuronal cells were identified by immunofluorescence staining with Neu-N (green fluorescence). Representative images of three independent experiments are shown. The star symbol indicates that the neuronal living cells are markedly decreased in hippocampus of CHOP−/− mice.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0040801.g007