Rapid Vascular Responses to Anthrax Lethal Toxin in Mice Containing a Segment of Chromosome 11 from the CAST/Ei Strain on a C57BL/6 Genetic Background
Figure 1
Evan’s blue leakage in lungs of B6.CAST.11M and C57BL/6J mice.
A) C57BL/6J mice given saline, B) B6.CAST.11M mice given saline, C) C57BL/6J mice given LT, and D) B6.CAST.11M mice given LT by i.p. injection were sacrificed 1 h post administration. Evan’s Blue fluoresces bright red under UV light. Evan’s Blue was more wide spread in B6.CAST.11M LT mice than in other groups. Scale bar = 50 µm. E) The average percent lung tissue section area stained with Evan’s Blue. Error bars represent standard error of the mean. C57BL/6J mice given saline (N = 5), B6.CAST.11M mice given saline (N = 10), C57BL/6J mice given LT (N = 8), B6.CAST.11M mice given LT (N = 13).