Efficacy of EGFR Inhibition Is Modulated by Model, Sex, Genetic Background and Diet: Implications for Preclinical Cancer Prevention and Therapy Trials
Figure 4
Western blot analysis of EGFR signal.
Total EGFR and pEGFR in liver protein lysates from A) APCMin/+ and B) AOM mice, separately for each strain and sex. STD = standard diet, WD = western diet, “+” = AG1478 treatment and “−“ = no AG1478 treatment. Below bar graphs are estimated effects and significance based on linear mixed models.