Role of Sphingomyelinase in Infectious Diseases Caused by Bacillus cereus
Figure 4
Effect of Bc-SMase on the infection with B. cereus or B. subtilis.
Mice received various concentrations of Bc-SMase and B. cereus (ATCC21928, 5×107 CFU/mouse). A) Mice were monitored every five hours after the injection. The duration of the experiment was set at 100 h. ○, B. cereus; □, 1.0 µg Bc-SMase; △, 5.0 µg Bc-SMase; ▴, 0.1 µg Bc-SMase + B. cereus; •, 1.0 µg Bc-SMase + B. cereus; ▪, 5.0 µg Bc-SMase + B. cereus. B) B. cereus in blood was cultured on Luria broth agar plates. Values represent the mean ± SEM; n = 5 independent experiments.