Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection
Figure 6
Growth phenotypes of the ΔpmcB mutant strain.
The A. fumigatus wild-type, ΔpmcB::pmcB and ΔpmcB mutant strains were grown for 72 hours at 37°C in (A)YAG, YAG+25 ng/ml cyclosporin (Cs), MM, or MM+25 ng/ml Cs; (B) YAG+500 mM CaCl2, YAG+25 ng/ml Cs+500 mM CaCl2, MM+500 mM CaCl2, or MM+25 ng/ml Cs+500 mM CaCl2; (C) YAG+25 mM MnCl2, YAG+25 ng/ml Cs+25 mM MnCl2, MM+25 mM MnCl2, or MM+25 ng/ml Cs+25 mM MnCl2.