Ablation of Sim1 Neurons Causes Obesity through Hyperphagia and Reduced Energy Expenditure
Figure 5
Ablation of Sim1 neurons reduces resting energy expenditure, body and BAT temperature.
Resting energy expenditure for individual mice was calculated as described in the results (A, n = 4 for each group, *p<0.05, **p<0.01). (B) Rectal temperature and BAT temperature were measured (n = 7 for each group, *p<0.05). Error bars indicate SEM for all figures. Means for each condition were compared using repeated measures two-way ANOVA with Bonferroni post-test (A) and a two-tailed t-test, with Welch's correction (B).