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How Linear Tension Converts to Curvature: Geometric Control of Bone Tissue Growth

Figure 2

Computational methods.

A-B - Principle of curvature measurement on continuous (A) and discrete (B) interfaces (adapted from [38]). The grey area represents the contributing area A in equation 1 where is the radius of the mask, in A and in B. C - Implementation of CCTG. The whole image is scanned with the mask (1−) and the ratio is attributed to each pixel (2−). A threshold of 0.5, corresponding to is applied: free pixels where are filled with tissue (3−). The interface is then updated and the entire procedure is repeated.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0036336.g002