Vagal Nerve Stimulation Rapidly Activates Brain-Derived Neurotrophic Factor Receptor TrkB in Rat Brain
Figure 1
Vagal nerve stimulation (VNS) rapidly induces TrkB activation in rat hippocampus.
Effects of acute (2 hr) VNS, desipramine (DMI, 10 mg/kg, i.p) or fluoxetine (15 mg/kg, i.p) on TrkB phosphorylation at different tyrosine residues in rat hippocampus.Phospho-TrkB values are normalized against total-TrkB values. One-way MANOVA, Student's Newman-Keuls post-hoc test, *P<0.05, n = 4−8 per group.