Gastrointestinal Microbiota Do Not Significantly Contribute to T Cell Activation or GI Inflammation in Ndfip1-cKO Mice
Figure 4
Ndfip1 CD4-cKO mice treated with antibiotics from birth do not show changes in eosinophilia or inflammation in the esophagus, or splenic T cell activation.
(A) Weights of control mice (n=4) (closed circles) or Ndfip1-cKO mice(n=4) (open circles) between weeks 3 to 5 of antibiotic treatment. (B) H & E stains of histological sections of esophagus taken from control and Ndfip1-cKO mice after antibiotic treatment from birth to 5 weeks. Images were taken using a 20× objective. Inset of panel outlined by the box is shown in the images on the right.