DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription
Figure 7
DOR mutants L36A/L40A or E97K/D98K localize in the nucleus.
Panel A. Expression of wild-type and mutant forms L36A/L40A or E97K/D98K of DOR. Western blot assays were performed in cell extracts by using specific antibodies against DOR and beta-actin. Panel B. Intracellular distribution of DOR mutants. HeLa cells were transiently transfected with wild-type or mutant forms L36A/L40A or E97K/D98K of DOR. The intracellular localization of DOR was analyzed by immunofluorescence and is shown in red. The nuclei are shown in blue (DAPI staining). Scale bars, 10 µm.