Changes in Plasma Membrane Surface Potential of PC12 Cells as Measured by Kelvin Probe Force Microscopy
Figure 3
PS-micelles altered the Φs distribution histogram.
Figures A and B show the AFM and KPFM images, respectively, of a PC12 cell treated with PS-micelles. C. The Φs from B was binned with 40 steps and the histogram was fitted with a two-peak Gaussian model (red line). The two Gaussian distributions were plotted in green and blue. D. Averaged skewness in PC12 cells without treatment (control) or treated with PC- and PS-micelles (PC & PS, respectively). Data are expressed as mean ± SEM, and N = 11 for each group. * indicates p<0.05 (by Student's t-test) compared with the control group.