Seminal Plasma Enhances Cervical Adenocarcinoma Cell Proliferation and Tumour Growth In Vivo
Figure 4
Upregulation of PTGS and PTGER expression in xenograft tumours in response to treatment with seminal plasma.
(A) PTGS1 and (B) PTGS2 mRNA expression was measured by quantitative RT-PCR and is significantly increased by SP (1∶500) as compared to the vehicle (PBS) control, (P<0.01** and P<0.001***) respectively. (C) PTGER1 (P<0.01**), (D) PTGER2 (P<0.05*), (E) PTGER3 (ns) and (F) PTGER4 (P<0.05*) mRNA expression levels of the 4 different subtypes of the PGE2 receptors as determined by quantitative RT-PCR analysis. Data are represented as mean ± SEM from SP (n = 6) or vehicle controls (n = 8).