The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease
Figure 6
Effect of the top six zinc binding sites on the tubulin electrostatic.
Rotation of the tubulin dimer in 90° increments from left to right. Top row – tubulin without zinc. Bottom row – tubulin with zinc at the top six sites, arrows indicate regions of change. Blue – positive charge, Red – negative charge, White – electrostatically neutral. Potential map ranges from −1 kT/e to 1 kT/e. Scale bar corresponds to 5 nm.