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Both TLR2 and TRIF Contribute to Interferon-β Production during Listeria Infection

Figure 1

PgdA-dependent IFN-β response to Listeria in peritoneal macrophages.

PEM from WT C57BL/6J mice were infected with the parental EGDe strain (black bars), the ΔpgdA mutant (grey bars) or the complemented ΔpgdA strain (white bars). After 7 h of infection, IFN-β levels were measured in supernatants by ELISA. Data are mean ± SD (***, p<0.0001, n = 5).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0033299.g001