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Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled Microgravity

Figure 4

miRNA changes in human irradiated PBL incubated 24 h in 1 g and in MMG.

A) The Venn Diagram shows the number of common and exclusively expressed miRNAs as a consequence of only radiation (0.2Gy 1 g, 2Gy 1 g) and radiation with microgravity (0.2Gy MMG, 2Gy MMG). B) miRNAs differentially expressed in PBL incubated 24 h in 1 g or MMG after irradiation with 0.2 and 2Gy. The expression level is given as log 2 (irradiated/non-irradiated) PBL incubated in the indicated gravity condition.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0031293.g004