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Reorganizing the Intrinsic Functional Architecture of the Human Primary Motor Cortex during Rest with Non-Invasive Cortical Stimulation

Figure 2

Global network metrics.

Shown are the results of the global network parameters that were calculated in the present study (mean connectivity degree (K) and the small-world parameters gamma, lambda and sigma [32]) calculated at each threshold T (0.25–0.35 in increasing steps of 0.002) before and after each Sham (A), Cathodal (B) and Anodal (C) tDCS. The second row - second column of each panel show that the approximate number of nodes (M1 voxels) of each undirected graph was ∼470. As expected, the mean connectivity degree monotonically decreases as T increases. M1 has salient small-world properties i.e. lambda≈1, gamma≫1, thus sigma≫1 [32], [41]. No significant differences were observed for any of the network metrics before and after each of the tDCS sessions (P>0.05 paired two-tailed t-tests). Error bars represent the s.e.m.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0030971.g002