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Dilated Thin-Walled Blood and Lymphatic Vessels in Human Endometrium: A Potential Role for VEGF-D in Progestin-Induced Break-Through Bleeding

Figure 8

Progestin effects on xenograft vessel density and area.

Blood vessel density decreases and lymphatic vessel cross sectional vessel area increases in human endometrial xenografts treated with medroxyprogesterone acetate (MPA). (A) Blood vessel density and (B) lymphatic vessel density of untreated (E only) and treated (MPA) xenografts. (C) Blood vessel and (D) lymphatic vessel cross sectional area of E only and MPA treated xenografts. Bars represent means ± SE. * P<0.05.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0030916.g008