HIV-Induced T-Cell Activation/Exhaustion in Rectal Mucosa Is Controlled Only Partially by Antiretroviral Treatment
Figure 3
T-cells from untreated patients exhibit elevated expression of PD-1 in rectal tissues.
A) Flow cytometry data from one representative experiment with GALT samples from healthy controls, HIV+ HAART-treated and untreated patients are shown. Percentage of CD4+PD-1+ cells and MFI is indicated in each panel. B) MFI of PD-1 in CD4+ (left panel) and CD8+ (right panel) T-cells from GALT.