Glucocorticoid Regulation of SLIT/ROBO Tumour Suppressor Genes in the Ovarian Surface Epithelium and Ovarian Cancer Cells
Figure 1
Expression analysis of the SLIT and ROBO gene families in human OSE (hOSE).
A) Light-field microscopy of ovary showing specific staining for SLIT2 (brown) in the OSE. B) Likewise positive ROBO1 (brown) staining was also observed in the OSE. C) No staining was observed in negative controls. Scale bars represent 100 µm. D) RT-PCR for SLITs and ROBOs in cultured hOSE. With the exception of SLIT1 and ROBO3 the members of the SLIT and ROBO families were expressed in hOSE. FB = Fetal Brain positive control; -RT = RT negative negative control.