Molecular Analysis of Virulent Determinants of Enterovirus 71
Figure 2
The predicted three dimensional structures of VP1 protein and protease 2A of EV71.
A: predicted three dimensional structure of VP1 protein. The left yellow ball represents the 145th amino acid residue (P710) at VP1, and the right one represents the 164th residue (P729) at VP1. B: predicted three dimensional structure of Protease 2A protein. The yellow ball represents the 68th residue (P930) at 2A protein. C: the comparison of DE loop between predicted VP1 structure of EV71 (BJ08-Z004-3) and the real structure of 4 other picornaviruses. The yellow tubes represent the DE loop, and the yellow balls represent the corresponding residue on each strain to the residue on VP1-145 of EV71. D: the comparison of EF loop between predicted VP1 structure of EV71 and the real structure of 4 other picornaviruses. The yellow tubes represent the EF loop, and the yellow balls represent the corresponding residue on each strain to the residue on VP1-164 of EV71.