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Gamma-Irradiated Influenza Virus Uniquely Induces IFN-I Mediated Lymphocyte Activation Independent of the TLR7/MyD88 Pathway

Figure 2

Generalized partial lymphocyte activation during A/PR8 infection is dose dependent.

Splenocytes from wild-type mice were analysed for CD69 expression on CD3+ cells 24h following i.v injection of variable doses of A/PR8. Dot plots show fluorescence profiles of A/PR8 infected compared to naïve mice.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0025765.g002