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Synapse Geometry and Receptor Dynamics Modulate Synaptic Strength

Figure 3

Glutamate dynamics in the extracellular space.

(A) Plot of the glutamate density in the extrasynaptic space for various times after vesicular release. Glial distance is 40 nm and transporter density is 5,000. (B, C) Clearance time and spreading distance is shown for various glial sheath distances from 10 nm to 100 nm and transporter densities from 2,500 to 5,000 to 10,000.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0025122.g003