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Immune Response to Bifidobacterium bifidum Strains Support Treg/Th17 Plasticity

Figure 3

Cytokine production by CD4+ T lymphocytes stimulated with Bifidobacterium treated DCs.

DCs maturated with LPS, B. bifidum LMG13195, L22, A8 and IF10/10 or B. breve BM12/11 were cocultured with allogeneic naïve CD4+CD45RA+ T cells at T-cell:DC ratio of 1∶10. The concentration of IL-10, IL-17, IFNγ and TNFα was quantified by multiplex assay. Bars represent the mean and standard deviation of four independent experiments performed with different blood donors.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0024776.g003