Immune Response to Bifidobacterium bifidum Strains Support Treg/Th17 Plasticity
Figure 3
Cytokine production by CD4+ T lymphocytes stimulated with Bifidobacterium treated DCs.
DCs maturated with LPS, B. bifidum LMG13195, L22, A8 and IF10/10 or B. breve BM12/11 were cocultured with allogeneic naïve CD4+CD45RA+ T cells at T-cell:DC ratio of 1∶10. The concentration of IL-10, IL-17, IFNγ and TNFα was quantified by multiplex assay. Bars represent the mean and standard deviation of four independent experiments performed with different blood donors.