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Severe Hindrance of Viral Infection Propagation in Spatially Extended Hosts

Figure 8

Phase diagrams for .

(a) Contour plot of the average replicative ability as a function of in the absence of beneficial mutations (). (b) in the plane when beneficial mutations are considered (). The initial replicative abilities are for . Two-site approximations to the critical thresholds are shown as black curves, whereas simulation results appear in a color scale coding for the average replicative ability . Insets correspond to cross-sections of the surface at (green curves). For we also show the dependence of with under the two-site approximation regime at fixed (red curve).

Figure 8

doi: https://doi.org/10.1371/journal.pone.0023358.g008