IgE-Mediated Enhancement of CD4+ T Cell Responses in Mice Requires Antigen Presentation by CD11c+ Cells and Not by B Cells
Figure 2
Diphtheria toxin depletes CD11c-DTR mice of CD11c+ cells.
CD11c-DTR mice were treated with 100 ng diphtheria toxin or left untreated. Twenty-four hours later total spleen cells were analyzed in flow cytometry and dendritic cells were defined as CD11c+, MHC-IIhi cells. The numbers show % of live cells in a representative experiment with 97% depletion of dendritic cells.