Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure
Figure 2
Transport of probe particles in saline- (Control) or MAP-exposed CVM.
(A) Sample trajectories of probe particles with effective diffusivities within one S.E.M. of the mean at a time scale of 1 s. (B) Ensemble-averaged geometric mean square displacements (<MSD>) as a function of time scale for probe particles. Data represent six independent experiments with samples from different donors (n≥100 particles per experiment). α represents the slope of the log-log <MSD> vs. time scale plot. * indicates statistical significance at p<0.05.