Sequence Imputation of HPV16 Genomes for Genetic Association Studies
Figure 1
A schematic representation of the HPV16 genome.
The 7,908 bp circular, double-stranded DNA genome of the HPV16 reference sequence is illustrated. Genes expressed early in the viral life cycle (early genes) are drawn with solid black lines and their names prefixed by an “E”. Genes expressed late in the viral life cycle (late genes) that encode the structural capsid proteins, are indicated by blue lines and have names prefixed by an “L”. The upstream regulatory region (URR) and a second non-coding region (NCR) are drawn in gray. The viral genome and positions within the DNA sequence are displayed by the helix and numbers, respectively.